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NAD+Your cells are aging faster than you are.

Nicotinamide Adenine Dinucleotide — the cellular energy molecule that declines with age. IV NAD+ therapy supports mitochondrial function, neurological health, metabolic repair, and longevity at the cellular level.

*Provided following a medical evaluation and physician oversight.

NAD+ IV Bag at TrufaMED
About This Treatment

What is
NAD+?

NAD+ is a coenzyme present in every cell of the body — essential for energy production, DNA repair, gene expression, and hundreds of metabolic processes. NAD+ levels decline naturally with age, and this decline is directly associated with reduced cellular energy, accelerated aging, cognitive decline, and metabolic dysfunction.

IV NAD+ therapy delivers this critical molecule directly to the bloodstream at therapeutic concentrations far beyond what oral supplements can achieve. It is one of the most scientifically compelling anti-aging and neurological wellness interventions available in clinical practice today.

2–4hr
Session Length
1
Pure NAD+
MD
Physician-Led
$999
Starting Price
The Formula

Key Ingredients.

🔬
NAD+ (Nicotinamide Adenine Dinucleotide)
A critical coenzyme in cellular energy production (ATP synthesis), DNA repair, sirtuin activation, and the regulation of hundreds of metabolic and longevity pathways throughout the body.
💧
Normal Saline Diluent
NAD+ is diluted in normal saline and administered slowly over several hours to maximize absorption, minimize side effects, and ensure the highest possible cellular uptake.
What It Does

Designed to Deliver.

Supports Cellular Energy Production
NAD+ is the essential cofactor for mitochondrial ATP synthesis — the fundamental energy currency of every cell. Restoring NAD+ levels directly improves cellular energy output throughout the body.
Promotes DNA Repair
NAD+ is required by PARP enzymes that repair DNA damage — addressing one of the core mechanisms of cellular aging and disease development at the molecular level.
Activates Longevity Pathways
NAD+ activates sirtuins — a family of proteins associated with longevity, stress resistance, and metabolic regulation — that are directly suppressed by age-related NAD+ decline.
Supports Brain & Neurological Health
NAD+ is critical for neuronal energy metabolism and neuroprotection. Patients frequently report improved cognitive clarity, focus, and mental resilience following NAD+ infusion.
Aids Metabolic & Addiction Recovery
NAD+ therapy has demonstrated clinical utility in supporting metabolic repair and neurochemical rebalancing during recovery from chronic stress, burnout, and substance dependence.
Anti-Aging at the Cellular Level
By addressing the fundamental molecular decline associated with aging — reduced NAD+, impaired mitochondrial function, accumulated DNA damage — this therapy targets aging itself, not just its symptoms.
The Experience

What to Expect.

1
Comprehensive Medical Evaluation
NAD+ therapy requires a thorough physician consultation to determine appropriate dosing, infusion rate, and whether a single or multi-session protocol is recommended for your goals.
2
Extended Infusion Setup
NAD+ must be administered slowly to avoid discomfort. Our clinical team monitors you throughout and adjusts the infusion rate based on your comfort and tolerance.
3
2–4 Hour Session
NAD+ infusions take significantly longer than standard IV therapies. Bring a book, use the time to rest, or simply let the process work. Many patients report feeling the effects during the infusion itself.
4
Post-Infusion Assessment
Our physician reviews how you're responding and recommends a follow-up protocol — many patients benefit most from a series of 3–5 sessions over consecutive days or weeks.
TrufaMED IV Therapy Session
Good to Know

The Molecule Behind Cellular Aging.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell of the human body. It plays a central role in energy metabolism, DNA repair, gene expression, and cellular signaling. Research has shown that NAD+ levels decline significantly with age — by as much as 50 percent between the ages of 40 and 60 — and this decline is increasingly linked to the hallmarks of aging, including cognitive decline, reduced energy, metabolic slowdown, and increased susceptibility to disease.

Restoring NAD+ levels through IV infusion is one of the most direct interventions available. Unlike oral NAD+ precursors such as NMN or NR, which must be converted through multiple enzymatic steps and are limited by digestive absorption, IV NAD+ delivers the molecule directly into the bloodstream at bioavailable concentrations. This allows cells to use it immediately for mitochondrial energy production, sirtuin activation, and PARP-mediated DNA repair.

The NAD+ IV has become one of the most sought-after longevity and performance treatments in modern wellness medicine. At TrufaMED in Surfside, we offer NAD+ infusions under physician supervision for patients interested in cognitive enhancement, anti-aging, addiction recovery support, and peak metabolic function.

Common Questions

Frequently Asked Questions.

What does NAD+ do in the body?

+
NAD+ is a coenzyme involved in hundreds of metabolic processes. Its primary roles include converting nutrients into cellular energy within mitochondria, activating sirtuins that regulate aging and inflammation, supporting DNA repair enzymes, and maintaining healthy cell-to-cell communication. As NAD+ levels decline with age, these processes become less efficient.

Why can't I just take NAD+ supplements orally?

+
Oral NAD+ is largely broken down during digestion and has very limited bioavailability. While precursors like NMN and NR can help support NAD+ production over time, they require enzymatic conversion and do not achieve the same rapid, direct increase in blood NAD+ levels that IV administration provides. For patients seeking immediate and measurable results, IV delivery is significantly more effective.

How long does the NAD+ infusion take?

+
NAD+ infusions take longer than most IV treatments because the molecule must be administered slowly to ensure comfort and tolerability. Expect the session to take two to four hours depending on the dose. Many patients use the time to work, read, or relax in our private treatment lounge.

What will I feel during the infusion?

+
Some patients experience sensations during the NAD+ infusion, including mild chest tightness, warmth, nausea, or an increased heart rate. These are normal physiological responses and typically resolve by adjusting the infusion rate. Our clinical team monitors you throughout and will adjust the drip speed to keep you comfortable.

How many NAD+ sessions do I need to see results?

+
Many patients report improved mental clarity, energy, and mood after their first session. For more sustained anti-aging and neurological benefits, a series of three to six initial sessions is often recommended, followed by monthly maintenance infusions. Your physician will design a protocol based on your specific goals.

Who is NAD+ therapy best for?

+
NAD+ therapy is popular among patients focused on longevity and anti-aging, those experiencing cognitive decline or brain fog, individuals recovering from addiction, athletes seeking enhanced recovery and performance, and anyone over 35 who wants to support their body's declining NAD+ levels proactively.

Is NAD+ IV therapy safe?

+
NAD+ is a naturally occurring molecule in the human body, and IV administration at therapeutic doses is considered safe when administered by trained medical professionals. All NAD+ sessions at TrufaMED are supervised by a physician, with vital sign monitoring throughout. A thorough medical evaluation is performed before your first treatment.

Ready to Book?

Physician-supervised. Private setting. Book your NAD+ session today.

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Pricing & Formulation

NAD+ IV Therapy Physician-supervised NAD+ at clinical doses for cellular energy and neurological recovery.

What's Inside

NAD+ (Nicotinamide Adenine Dinucleotide)
Clinical-dose NAD+ — the core coenzyme involved in mitochondrial energy production, DNA repair, and cellular signaling. Dosing tailored by your physician.
B-Complex (B1, B2, B3, B5, B6, B12)
Cellular energy support and neurological function. NAD+ depletion drives fatigue; B-complex amplifies recovery.
Methylated B12
Active form of B12 for nervous system support and methylation pathway optimization.
Magnesium
Mitigates infusion-related muscle tension. Improves comfort during long infusions.
500mL IV Saline Carrier
Slow-drip carrier base. NAD+ requires slow administration for tolerability.
Anti-Nausea Pre-Medication (if needed)
Available on request to manage transient flushing or GI symptoms common with NAD+ infusions.
Best for: Adults focused on longevity, cognitive performance, post-concussion recovery, addiction recovery support, chronic fatigue, or pre/post-surgical neurological optimization. Mobile NAD+ delivery is $1,250 (special rate — not the standard +$50 mobile uplift).

Why NAD+ at Clinical Dose Matters

NAD+ is the central coenzyme that powers mitochondrial ATP production, sirtuin activity (the longevity gene family), and PARP-mediated DNA repair. NAD+ levels decline measurably with age, chronic stress, alcohol use, and post-viral states like Long COVID — and that decline is now considered a primary driver of accelerated cellular aging.

Oral NAD+ precursors (NMN, NR) are absorbed inconsistently and require months of consistent dosing to meaningfully shift intracellular levels. IV NAD+ at 1,000 mg saturates the bloodstream directly and produces measurable shifts in cellular NAD+ within a single session. This is why TrufaMED's NAD+ protocol is delivered as a slow 3–4 hour infusion under continuous physician oversight — it is a clinical procedure, not a wellness drip.

Who Sees the Strongest Response

Patients on structured longevity protocols — typically 4 to 6 NAD+ infusions over 4 to 6 weeks paired with HBOT and lifestyle optimization — report the most consistent gains in mental clarity, energy, and sleep architecture. Post-concussion patients often pair NAD+ with HBOT cognitive protocols. Addiction-recovery patients (alcohol, opioid) may receive NAD+ as part of a structured taper protocol coordinated with their addiction medicine physician.

What to Expect During Infusion

NAD+ is infused slowly because faster delivery causes pronounced flushing, chest tightness, and nausea. Your physician calibrates the drip rate to your tolerance — most patients settle into a comfortable rhythm within the first 30 minutes. You can read, work, or rest during the infusion. Red Light Therapy is included free with every in-clinic NAD+ session.

Pricing
$999
Session Length3-4 hours (slow infusion)
Physician SupervisedYes
DeliveryClinic or Mobile
Book in Clinic Book Mobile Delivery

Common Questions About NAD+ IV Therapy

How is IV NAD+ different from oral NMN or NR supplements?
IV NAD+ delivers full clinical doses directly to circulation. Oral NMN and NR are precursors that the body converts to NAD+ — absorption is variable and intracellular gains take months of consistent dosing to match what one IV infusion delivers acutely.
How many NAD+ sessions do I need?
Most longevity and cognitive performance protocols at TrufaMED are 4 to 6 sessions over 4 to 6 weeks, with optional maintenance every 4 to 8 weeks thereafter. Your physician adjusts based on your goals and response.
Why does NAD+ take so long to infuse?
NAD+ at clinical doses requires slow administration — faster infusion causes flushing, chest tightness, and nausea. The 3-4 hour duration is the protocol that maximizes both tolerability and cellular uptake.
Can I get NAD+ delivered to my home?
Yes — TrufaMED offers mobile NAD+ infusion at $1,250 (this is a special rate — not the standard +$50 mobile uplift). Sessions still require 3 to 4 hours and full physician oversight.
Pricing & Formulation

NAD+ IV Therapy Physician-supervised NAD+ at clinical doses for cellular energy and neurological recovery.

What's Inside

NAD+ (Nicotinamide Adenine Dinucleotide)
Clinical-dose NAD+ — the core coenzyme involved in mitochondrial energy production, DNA repair, and cellular signaling. Dosing tailored by your physician.
B-Complex (B1, B2, B3, B5, B6, B12)
Cellular energy support and neurological function. NAD+ depletion drives fatigue; B-complex amplifies recovery.
Methylated B12
Active form of B12 for nervous system support and methylation pathway optimization.
Magnesium
Mitigates infusion-related muscle tension. Improves comfort during long infusions.
500mL IV Saline Carrier
Slow-drip carrier base. NAD+ requires slow administration for tolerability.
Anti-Nausea Pre-Medication (if needed)
Available on request to manage transient flushing or GI symptoms common with NAD+ infusions.
Best for: Adults focused on longevity, cognitive performance, post-concussion recovery, addiction recovery support, chronic fatigue, or pre/post-surgical neurological optimization. Mobile NAD+ delivery is $1,250 (special rate — not the standard +$50 mobile uplift).

Why NAD+ at Clinical Dose Matters

NAD+ is the central coenzyme that powers mitochondrial ATP production, sirtuin activity (the longevity gene family), and PARP-mediated DNA repair. NAD+ levels decline measurably with age, chronic stress, alcohol use, and post-viral states like Long COVID — and that decline is now considered a primary driver of accelerated cellular aging.

Oral NAD+ precursors (NMN, NR) are absorbed inconsistently and require months of consistent dosing to meaningfully shift intracellular levels. IV NAD+ at 1,000 mg saturates the bloodstream directly and produces measurable shifts in cellular NAD+ within a single session. This is why TrufaMED's NAD+ protocol is delivered as a slow 3–4 hour infusion under continuous physician oversight — it is a clinical procedure, not a wellness drip.

Who Sees the Strongest Response

Patients on structured longevity protocols — typically 4 to 6 NAD+ infusions over 4 to 6 weeks paired with HBOT and lifestyle optimization — report the most consistent gains in mental clarity, energy, and sleep architecture. Post-concussion patients often pair NAD+ with HBOT cognitive protocols. Addiction-recovery patients (alcohol, opioid) may receive NAD+ as part of a structured taper protocol coordinated with their addiction medicine physician.

What to Expect During Infusion

NAD+ is infused slowly because faster delivery causes pronounced flushing, chest tightness, and nausea. Your physician calibrates the drip rate to your tolerance — most patients settle into a comfortable rhythm within the first 30 minutes. You can read, work, or rest during the infusion. Red Light Therapy is included free with every in-clinic NAD+ session.

Pricing
$999
Session Length3-4 hours (slow infusion)
Physician SupervisedYes
DeliveryClinic or Mobile
Book in Clinic Book Mobile Delivery

Common Questions About NAD+ IV Therapy

How is IV NAD+ different from oral NMN or NR supplements?
IV NAD+ delivers full clinical doses directly to circulation. Oral NMN and NR are precursors that the body converts to NAD+ — absorption is variable and intracellular gains take months of consistent dosing to match what one IV infusion delivers acutely.
How many NAD+ sessions do I need?
Most longevity and cognitive performance protocols at TrufaMED are 4 to 6 sessions over 4 to 6 weeks, with optional maintenance every 4 to 8 weeks thereafter. Your physician adjusts based on your goals and response.
Why does NAD+ take so long to infuse?
NAD+ at clinical doses requires slow administration — faster infusion causes flushing, chest tightness, and nausea. The 3-4 hour duration is the protocol that maximizes both tolerability and cellular uptake.
Can I get NAD+ delivered to my home?
Yes — TrufaMED offers mobile NAD+ infusion at $1,250 (this is a special rate — not the standard +$50 mobile uplift). Sessions still require 3 to 4 hours and full physician oversight.