Niagen IV Therapy
in Miami

Niagen is a patented, pharmaceutical-grade form of nicotinamide riboside chloride, a vitamin B3 molecule that acts as a direct precursor to NAD+. At TrufaMED it is given exclusively as a 500 mg IV over about sixty minutes, delivered by a registered nurse in our Surfside lounge under physician oversight. Niagen IV is a wellness and longevity service, not a treatment for any disease.

An NAD+ IV delivers the NAD+ molecule itself, a large coenzyme that has to be infused slowly over three to four hours and can bring flushing or chest pressure. A Niagen IV delivers nicotinamide riboside, a smaller B3 molecule that passes through the cell wall directly and is converted to NAD+ inside the cell. Published clinical evaluation of a 500 mg IV Niagen dose measured roughly 20% higher NAD+ at three hours versus baseline, with no attributable adverse events, in a session of about 60 minutes. Niagen does not replace NAD+ IV; the two work through different mechanisms and we offer both.

No. TrufaMED administers Niagen exclusively at 500 mg and does not offer a reduced-dose tier. The clinical evaluation that supports Niagen IV used the 500 mg dose, and we keep every session at full strength rather than offering a partial one. If 500 mg Niagen is not the right fit, your physician may recommend our NAD+ IV program instead.

A 500 mg Niagen IV runs about sixty minutes including setup, roughly 75% shorter than a standard NAD+ IV, which typically takes 180 to 240 minutes. Most patients work, read, or rest during the infusion, with complimentary red light therapy running alongside.

The first clinical evaluation of a 500 mg IV Niagen dose reported no attributable adverse events. In our experience most patients have no flushing, no chest pressure, and no nausea, which are the three discomforts most often reported on a conventional NAD+ IV. Occasional mild warmth at the infusion site can occur. Niagen IV is not appropriate for patients with current or prior cancer, pregnancy, breastfeeding, active rheumatoid arthritis, or a known hypersensitivity, all of which are screened during intake.

A typical longevity-maintenance cadence is monthly to every other week. Most TrufaMED patients settle into one or two sessions a month. Your physician recommends a schedule after your intake based on your goals, your response, and biomarker monitoring. Our package of four is built around a quarterly arc, usually four sessions spaced two to four weeks apart.

Niagen is sold as a package of four 500 mg sessions for $3,200, which works out to $800 per session. A single session is $1,200. Niagen IV is also included as part of the TrufaMED Concierge Signature membership. It is a self-pay wellness service and is not covered by insurance. We accept major credit cards, FSA, and HSA.

Yes. NAD+ IV remains on the TrufaMED longevity menu at $1,000 per session in-clinic. Niagen IV is our newer flagship NAD+-pathway protocol, but a direct NAD+ IV stays available for patients who specifically want direct NAD+ replenishment or who prefer to combine both therapies in sequence. Your physician helps design the protocol that fits your goals.

Niagen injectable is a compounded drug prepared by a licensed US compounding pharmacy and is not an FDA-approved therapeutic. It is dispensed for office use only under an active physician standing order. Nicotinamide riboside as a raw ingredient is a generally recognized safe dietary form of vitamin B3. Adverse events are reported to fda.gov/medwatch.

Yes. The 500 mg Niagen IV is available in our Surfside lounge and as a mobile registered-nurse visit across South Florida, including Miami Beach, Bal Harbour, Sunny Isles Beach, Bay Harbor Islands, Aventura, and Brickell. Book in-clinic online, or arrange a mobile visit through our mobile IV service.

Most patients describe a clean, steady lift in energy and clarity during the infusion and for hours afterward. The biochemical endpoint cited in clinical evaluation, about 20% higher NAD+ versus baseline, peaks near the three-hour mark after infusion. The cumulative longevity benefit builds over a consistent monthly or biweekly cadence, which is why most patients choose the package of four. Individual response varies.

Niagen IV is administered only after a physician-supervised intake. It is avoided in patients with a current or prior history of cancer, pregnancy or breastfeeding, active rheumatoid arthritis, or a known hypersensitivity to nicotinamide riboside. Patients on diabetes medications, blood thinners, or with chronic kidney or liver disease are reviewed individually. A complete history and medication list are checked before every first session.